PT-141
PT-141
PT-141 (bremelanotide) is a synthetic melanocortin receptor agonist studied in laboratory research for its interaction with MC3R and MC4R receptor pathways. Researchers investigate PT-141 to better understand melanocortin receptor signaling dynamics and peptide-mediated activation of central melanocortin system components. Experimental studies examine PT-141's receptor binding profiles, signaling cascade activation patterns, and downstream pathway modulation in controlled research models. These investigations contribute to broader scientific research focused on melanocortin receptor pharmacology and peptide-receptor interaction mechanisms. PT-141 continues to be examined in laboratory environments studying melanocortin signaling biology and receptor activation specificity. For research use only. Not for human consumption.
Research this compound
For research use only. Not for human consumption.
Identity, storage, and what ships.
The technical record. Identity rows reflect literature-cited values for this compound; storage rows describe the conditions under which Nexara holds and ships the lyophilized form.
Identity
- Appearance
- White lyophilized powder
- Molecular Formula
- C50H68N14O10
- Molecular Weight
- 1,025.18 g/mol
- CAS Number
- 189691-06-3
- Sequence
- Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
- Synonyms
- Bremelanotide, PT-141
- Purity
- ≥99%
Storage profile
- Storage (Lyophilized)
- -20°C (long-term), 2-8°C up to 30 days (short-term)
- Storage (Reconstituted)
- 2-8°C
- Shelf Life (Lyophilized)
- 24 months at -20°C
- Shelf Life (Reconstituted)
- Up to 28 days at 2-8°C
- Reconstitution
- Bacteriostatic water (0.9% benzyl alcohol) for research reconstitution
- Handling
- Light-sensitive. Store in opaque container and protect from direct light during handling. Avoid repeated freeze-thaw cycles.
Shipment
- —1x lyophilized vial (10mg)
- —Certificate of Analysis (upon request)
- —Storage instructions
Studied research areas.
Each item below names a domain in which PT-141 has been investigated in published research. Listed for context — not as a use recommendation.
- 01Melanocortin receptor signaling research
- 02MC3R/MC4R pathway studies
- 03Central melanocortin system analysis
- 04Receptor agonist binding dynamics
Held to research-grade quality standards.
Every batch is held to research-grade quality standards before it ships. Each vial is labeled with its batch identifier so that fulfillment can be traced through the order record. For our research-use-only posture, see the Research Compliance page.
Common questions for PT-141.
For research use only. Not for human consumption.
These products are not intended to diagnose, treat, cure, or prevent any disease. They are sold strictly as research chemicals for laboratory use.
Fulfillment:Orders ship from Texas via USPS once payment is confirmed. You'll receive tracking by email when your package leaves our facility.
Researcher reviews
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Reference reading on PT-141 and adjacent topics.
- 3 min
Compound profile
PT-141: Compound Profile
A research profile of PT-141, a cyclic melanocortin peptide that preferentially engages the MC3R and MC4R receptors: identity, the receptor mechanism, and its relationship to Melanotan-2.
- 4 min
Foundational
Melanocortin-System Peptides: A Research Overview
How the melanocortin peptide class is studied: PT-141 and Melanotan-2, the melanocortin receptor family (MC1R–MC5R) they act on, and what the receptor-signaling literature examines.
- 6 min
Lyophilization and Reconstitution: A Research Primer
Lyophilization-induced aggregation: how to recognize it
How aggregation arises during the lyophilization process, what it does to a peptide's functional behavior on reconstitution, and the visual and analytical signals that flag it.