MOTS-c
MOTS-c
MOTS-c is a mitochondria-derived peptide encoded within mitochondrial DNA and studied for its involvement in cellular signaling pathways associated with mitochondrial communication systems. Laboratory research explores how mitochondrial peptides participate in intracellular communication processes between mitochondria and nuclear signaling networks. Experimental studies examine cellular response pathways and regulatory mechanisms related to mitochondrial-derived signaling molecules. MOTS-c continues to be studied in experimental models focused on mitochondrial signaling biology and peptide-mediated cellular communication systems.
Research this compound
For research use only. Not for human consumption.
Identity, storage, and what ships.
The technical record. Identity rows reflect literature-cited values for this compound; storage rows describe the conditions under which Nexara holds and ships the lyophilized form.
Identity
- Appearance
- White lyophilized powder
- Molecular Formula
- C100H152N24O29S2
- Molecular Weight
- 2,174.49 Da
- CAS Number
- 1627580-64-6
- Sequence
- Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
- Synonyms
- Mitochondrial ORF-12, MOTS-c
- Purity
- ≥99%
Storage profile
- Storage (Lyophilized)
- -20°C (long-term), 2-8°C up to 30 days (short-term)
- Storage (Reconstituted)
- 2-8°C
- Shelf Life (Lyophilized)
- 24 months at -20°C
- Shelf Life (Reconstituted)
- Up to 28 days at 2-8°C
- Reconstitution
- Bacteriostatic water (0.9% benzyl alcohol) for research reconstitution
- Handling
- Protect from direct light. Avoid repeated freeze-thaw cycles.
Shipment
- —1x lyophilized vial (10mg)
- —Certificate of Analysis (COA)
- —Proper storage instructions
Studied research areas.
Each item below names a domain in which MOTS-c has been investigated in published research. Listed for context — not as a use recommendation.
- 01Mitochondrial-derived peptide signaling research
- 02Intracellular mitochondria-nucleus communication studies
- 03Cellular response pathway investigation
- 04Mitochondrial signaling biology research
- 05Peptide-mediated cellular communication studies
Held to research-grade quality standards.
Every batch is held to research-grade quality standards before it ships. Each vial is labeled with its batch identifier so that fulfillment can be traced through the order record. For our research-use-only posture, see the Research Compliance page.
Common questions for MOTS-c.
For research use only. Not for human consumption.
These products are not intended to diagnose, treat, cure, or prevent any disease. They are sold strictly as research chemicals for laboratory use.
Fulfillment:Orders ship from Texas via USPS once payment is confirmed. You'll receive tracking by email when your package leaves our facility.
Researcher reviews
Reviews open as orders are delivered.
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Reference reading on MOTS-c and adjacent topics.
- 3 min
Compound profile
MOTS-c: Compound Profile
A research profile of MOTS-c, a mitochondrial-derived signaling peptide encoded in mitochondrial DNA: identity, the AMPK metabolic mechanism, and what the literature studies.
- 4 min
Foundational
Mitochondrial-Targeted Peptides: A Research Overview
How the mitochondrial peptide class is studied: SS-31, a cardiolipin-targeting tetrapeptide, and MOTS-c, a mitochondrial-derived signaling peptide — two distinct routes to the same organelle.
- 6 min
Cold-Chain Logistics for Research Peptide Shipping
Lyophilized peptide stability at room temperature
How long lyophilized research peptides actually tolerate room temperature, why the answer depends on the sequence, and what the published stability literature says about real worst-case shipping exposures.
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